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Risk and Prevention of Herpes Zoster in Patients with Chronic Kidney Disease 慢性腎病病人的帶狀疱疹風險與預防

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Risk and Prevention of Herpes Zoster in Patients with Chronic Kidney Disease 慢性腎病病人的帶狀疱疹風險與預防

2026/1/29

What is Herpes Zoster (Shingles)?

  • Herpes zoster occurs when the varicella-zoster virus, which causes chickenpox, reactivates in nerve ganglia during periods of weakened immunity.
  • Shingles itself is not contagious, but the virus can spread to individuals who have never had chickenpox or received the chickenpox vaccine.
  • High-risk groups include:
    • Chronic kidney disease (CKD) patients
    • People with diabetes
    • Cardiovascular disease patients
    • Adults aged 50 and above
    • Individuals with a history of shingles
    • Those under high stress or with irregular lifestyles
  • Complications: About 30% of patients develop postherpetic neuralgia, which can cause pain lasting for months or even years.

Why Should CKD Patients Be Concerned?

  • Reduced kidney function often correlates with weakened immunity, increasing the risk of shingles.
  • CKD patients who develop shingles have a higher risk of requiring dialysis.
  • Dialysis patients have 3.29 times higher risk of shingles compared to the general population.

How to Prevent Shingles?

  • Maintain a balanced diet and regular exercise
  • Ensure good sleep habits and stress reduction
  • Get vaccinated against shingles

Shingles Vaccine Information

  • Consult your doctor before vaccination, especially if you are undergoing immunosuppressive therapy.
  • Administration: Two intramuscular doses, spaced 2–6 months apart
  • Recommended for:
    • Adults aged 50 and above
    • Adults aged 18 and above who are at high risk
  • Effectiveness:
    • Preventing shingles: 97% (ages 50–59), 91% (ages ≥70)
    • Preventing postherpetic neuralgia: 91% (ages ≥50)
  • Duration of protection: 87.7% efficacy even 11 years after vaccination
  • Side effects: Fatigue, fever, injection site pain

Quick Self-Check

Please check the following to assess your knowledge and attitude toward shingles:

  1. Do you know what shingles is?
    ☐ Yes ☐ No
  2. Do you know CKD patients have a higher risk of shingles?
    ☐ Yes ☐ No
  3. Do you know shingles can be prevented by vaccination?
    ☐ Yes ☐ No
  4. Are you willing to get the shingles vaccine?☐ Yes ☐ No ☐ Considering
Reference
製作單位:內科部腎臟系 編碼:HE-10320-E
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